Objective To analyze the spatial and temporal distribution characteristics of dengue fever (DF) in Guangdong province, China during 2006-2011 and to provide a scientific basis for the prevention and control of dengue. Methods The annual incidence of DF in the county-level areas (counties or districts) of Guangdong province was determined during 2006-2011. The geographic pattern of DF incidence was examined by spatial autocorrelation analysis. Results The incidence rates of DF in the Pearl River Delta region and Han River Delta region were >4/105 and >2.5/105, respectively. Moran'sⅠ statistics of DF distribution were significant from 2006 to 2007 (P=0.005) and from 2009 to 2011 (P=0.001), but it was not significant from 2007 to 2008 (P=0.814). Conclusion The risk of DF is not randomly distributed among the county-level areas in Guangdong province, and the Pearl River Delta region and Han River Delta region are high-risk areas.

【Abstract】 Objective The species of rodents was investigated along the Qinghai-Tibet Railway in representative areas where Norway rats (Rattus norvegicus) might be distributed in Tibetan Autonomous Region. Methods Rodents were trapped by snap trap, live trap and glue boards in different habitats in Lhasa, Nagqu and Nyingchi. The rodents captured were identified, then the densities and population constitutes of them were calculated. Results A total of 126 rodents were captured with 1817 snap traps. R.norvegicus did not be captured in the areas investigated. R.tanezumi was the dominant specie in Lhasa and Nyingchi, accounting for 84.1% and 70.0% respectively, while Mus musculus in Nagqu accounted for 98.1%. Conclusion The dominant species of rodents are R.tanezumi and M.musculus in the residential areas investigated, and no R.norvegicus was found.

Objective Establishing the infective model of BALB/c and KM mice with Bartonella henselae in the lab, inspecting the dynamic variety of bacteremia and IgG andtibody in the mice. Methods BALB/c and KM mice were inoculated with B.henselae by routes intraperitoneally with a dose of 2.5×10 ⁸ cfu/ml, Enzyme-linked immunosorbent assay(ELISA) of serum samples collected as early as 2 d after infection indicated humoral immune responses to B.henselae. Results Specific humoral responses remained through 36 d. From the 6 d PI, the value of A begain to drive up, and the climax was in the 36 d. Culture analysis of blood from mice infected with B.henselae yielded positive results 2 d after infection, and the cultures was detected by polymerase chain reaction by 2 d and up to 36 d. Conclusion Analysis of samples revealed induction of B.henselae-specific immunoglobulin G from 6 to 36 d after infection.

Objective Community composition of rodents was investigated in different habitats in Wulan county,Qinghai province,to primarily know whether Rattus norvegicus imported into west of Qinghai along the first project of Qinghai-Xizang Railway which is from Xining to Ge'ermu in Qinghai province,so as to provide basic evidence for future study of rodents species shift. Methods Rodents were captured with snap trap and live trap in different habitats of Wulan county,and then species were identified. Results Totally,1002 snap traps and 746 live traps were used and 168 small mammals were captured,of which 7 were pika ( Ochotona thomasi) and others were rodents belonging to 8 species: Cricetulus longicaudatus, Mus musculus, Microtuss oeconomus, Meriones meridianus, Allactaga sibirica, Phodopus roborovskii, Apodemus latronum, Myospalax fontanierii. In the residential area of the town, M.musculus was the dominant species; while in the farmland and forest nursery, C.longicaudatus and M.meridianus were more popular. The density of rodents in steppe was the lowest in all habitats. No R.norvegicus was found in residential areas and farmland around the town investigated. Conclusion There is no nature population of R.norvegicus in Wulan county of Qinghai province more than 20 years after the first project of Qinghai-Xizang Railway was open to traffic. More studies and long term surveillance should be done to confirm whether R.norvegicus will invade into the central area of Qinghai-Tibet plateau.